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Patents are a strong indicator of the innovative research performed by universities around the world. US patents remain the most valued patents in the world because of the size of the economy. 

In 2021 the University of California system with its 9 campuses took the top spot among all universities globally. With 671 US utility patents issued, it ranked number one amongst all universities and number 67 overall in the world. It was followed by two other university systems, State University System of Florida with 419 patents came in at number two and MIT with 402 patents was at the number 3 spot. One could argue that with the university systems reporting their patents together is not a fair comparison to the other universities which report their numbers on their own. MIT ranked #1 among individual universities reporting the highest number of US patents issued in 2021, followed closely by Harvard University and Stanford University.

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